Interleukin-19

Interleukin-19 (IL-19) is a protein that in humans is encoded by the IL19 gene. It is a member of the interleukin family, a group of cytokines that play a central role in the regulation of the immune system.

Structure and Function

Interleukin-19 is a secreted protein that belongs to the IL-10 family of cytokines. It is produced by monocytes and B cells and has been shown to stimulate the proliferation and activation of T cells and NK cells. IL-19 also plays a role in the regulation of inflammatory responses and autoimmune diseases.

Clinical Significance

Interleukin-19 has been implicated in a variety of diseases, including rheumatoid arthritis, psoriasis, and asthma. It has been shown to promote inflammation and tissue damage in these conditions. In addition, IL-19 has been identified as a potential therapeutic target for the treatment of these diseases.

Research

Research into the role of IL-19 in disease is ongoing. Current studies are focused on understanding the molecular mechanisms by which IL-19 contributes to inflammation and tissue damage, as well as developing therapies that target IL-19.

See Also

• Interleukin
• Cytokine
• Immune system
• Inflammation
• Autoimmune disease