Interlobular
Interlobular refers to the space or connective tissue between the lobules of an organ. In the context of the kidney, the term "interlobular" is often used to describe the arteries and veins that run between the renal lobules. Similarly, in the liver, "interlobular" refers to the bile ducts, arteries, and veins that run between the hepatic lobules.
Anatomy[edit | edit source]
In the kidney, the interlobular arteries and veins are branches of the arcuate arteries and veins that run through the renal cortex, supplying blood to the renal lobules. These vessels are responsible for delivering oxygenated blood to the nephrons, the functional units of the kidney, and carrying away deoxygenated blood and waste products.
In the liver, the interlobular bile ducts, arteries, and veins form the portal triad, a key component of the hepatic lobule. The interlobular bile ducts carry bile away from the liver cells to the gallbladder for storage and eventual release into the small intestine. The interlobular arteries deliver oxygenated blood to the liver cells, while the interlobular veins carry away deoxygenated blood and waste products.
Function[edit | edit source]
The interlobular structures in both the kidney and liver play crucial roles in the function of these organs. In the kidney, the interlobular arteries and veins are involved in the filtration of blood and the production of urine. In the liver, the interlobular bile ducts, arteries, and veins are involved in the production and transport of bile, the metabolism of nutrients, and the detoxification of harmful substances.
Clinical significance[edit | edit source]
Disease or damage to the interlobular structures can have serious implications for organ function. For example, blockage of the interlobular arteries in the kidney can lead to renal ischemia and acute kidney injury. Similarly, obstruction of the interlobular bile ducts in the liver can result in cholestasis, a condition characterized by the accumulation of bile in the liver.
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Contributors: Prab R. Tumpati, MD