Interlobular arteries

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Interlobular Arteries[edit | edit source]

Diagram of the kidney showing interlobular arteries.

The interlobular arteries are small branches of the renal artery that play a crucial role in the blood supply to the kidney. These arteries are essential for the proper functioning of the kidney, as they deliver oxygenated blood to the nephrons, the functional units of the kidney.

Anatomy[edit | edit source]

The interlobular arteries arise from the arcuate arteries, which are located at the border between the renal cortex and the renal medulla. As the arcuate arteries arch over the base of the renal pyramids, they give off several interlobular arteries that extend into the cortex.

The interlobular arteries run radially through the cortex towards the surface of the kidney. As they ascend, they give off numerous branches called afferent arterioles, which supply blood to the glomeruli. The glomeruli are networks of capillaries where the filtration of blood takes place, initiating the process of urine formation.

Function[edit | edit source]

The primary function of the interlobular arteries is to supply blood to the nephrons. Each interlobular artery serves a specific region of the renal cortex, ensuring that all parts of the kidney receive an adequate blood supply. The blood delivered by these arteries is rich in oxygen and nutrients, which are vital for the metabolic activities of the renal cells.

After passing through the glomeruli, the blood exits via the efferent arterioles, which then form a network of capillaries known as the peritubular capillaries and the vasa recta. These capillaries are involved in the reabsorption and secretion processes that occur in the nephron.

Clinical Significance[edit | edit source]

The interlobular arteries can be affected by various pathological conditions. For instance, in hypertension, the walls of these arteries may thicken, leading to reduced blood flow to the nephrons and potentially causing renal ischemia. In severe cases, this can contribute to the development of chronic kidney disease.

Additionally, diseases such as atherosclerosis can lead to the narrowing or blockage of the interlobular arteries, further compromising renal function. Understanding the anatomy and function of these arteries is crucial for diagnosing and managing renal vascular diseases.

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Contributors: Prab R. Tumpati, MD