Isopimaric acid
Isopimaric acid is a type of resin acid, a group of terpenoid compounds that are found in the resin of coniferous trees. It is a diterpene acid that is primarily derived from the pine tree species.
Chemical Structure[edit | edit source]
Isopimaric acid has a chemical formula of C20H30O2. It is a monocarboxylic acid that consists of three fused six-membered rings, with two methyl groups at positions 4 and 4', and a carboxylic acid group at position 19. The structure is similar to other resin acids, such as abietic acid and levopimaric acid, but with different positions of the double bonds and methyl groups.
Properties[edit | edit source]
Isopimaric acid is a white crystalline solid at room temperature. It is soluble in organic solvents such as ethanol, acetone, and chloroform, but insoluble in water. It has a melting point of 185-187 degrees Celsius and a boiling point of 391.5 degrees Celsius at 760 mmHg.
Biological Activity[edit | edit source]
Isopimaric acid has been found to exhibit several biological activities. It has antimicrobial properties, being effective against a range of bacteria and fungi. It also has anti-inflammatory properties, reducing the production of pro-inflammatory cytokines in cells. Additionally, it has been found to have antioxidant activity, protecting cells from damage by free radicals.
Uses[edit | edit source]
Isopimaric acid is used in the manufacture of varnish and printing ink. It is also used in the production of rosin for use in the paper industry. In addition, it is used in the synthesis of other chemicals, such as perfumes and flavoring agents.
Safety[edit | edit source]
Isopimaric acid is generally considered safe, but it can cause skin irritation and eye damage. It is recommended to handle it with appropriate protective equipment.
See Also[edit | edit source]
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Contributors: Prab R. Tumpati, MD