Isorhamnetol

Isorhamnetol

Isorhamnetol is a bioflavonoid, specifically an O-methylated flavonol, that is found in various plants, including grapevine and wine. It is a metabolite of quercetin and is absorbed in the small intestine with the aid of glucuronidase, an enzyme that breaks down glucuronides.

Chemical Structure

Isorhamnetol has the chemical formula C16H12O6 and a molecular weight of 300.26 g/mol. Its systematic name is 3,5,4'-Trihydroxy-3'-methoxyflavone. The structure consists of a flavone backbone, which is a 15-carbon skeleton consisting of two phenyl rings (A and B) and a heterocyclic ring (C). This structure is common to all flavonoids. The 3',5,4'-trihydroxy and 3'-methoxy functional groups are responsible for the compound's bioactivity.

Sources

Isorhamnetol is found in a variety of plants, including the skins of grapes, in wine, and in the medicinal plant Ginkgo biloba. It is also found in the olive plant, and in the Aloe vera plant.

Health Benefits

Isorhamnetol has been studied for its potential health benefits. It has been found to have antioxidant properties, which means it can neutralize harmful free radicals in the body. It also has anti-inflammatory properties, and may help to reduce inflammation in the body. Some studies have also suggested that isorhamnetol may have anticancer properties, although more research is needed in this area.

See Also

• Flavonoid
• Quercetin
• Grapevine
• Wine
• Ginkgo biloba
• Olive
• Aloe vera