JWH-130

From WikiMD's Food, Medicine & Wellness Encyclopedia

JWH-130 is a synthetic cannabinoid from the naphthoylindole family, which acts as a potent agonist at both the CB1 and CB2 receptors, with a slight preference for CB2. It was discovered by and named after Dr. John W. Huffman.

Chemistry[edit | edit source]

JWH-130 is part of the naphthoylindole family of synthetic cannabinoids. It is structurally related to compounds such as JWH-018 and JWH-073, which are also potent agonists of the CB1 and CB2 receptors.

Pharmacology[edit | edit source]

JWH-130 acts as a potent agonist at both the CB1 and CB2 receptors, with a slight preference for CB2. The CB1 receptor is primarily located in the brain, and is responsible for the psychoactive effects of cannabinoids. The CB2 receptor is primarily found in the immune system, and is involved in a variety of physiological processes.

Effects[edit | edit source]

The effects of JWH-130 are similar to those of other synthetic cannabinoids and include psychoactive effects, analgesic effects, and anti-inflammatory effects. However, the exact effects can vary depending on the individual and the dose.

Legal Status[edit | edit source]

The legal status of JWH-130 varies by country. In some countries, it is classified as a controlled substance, while in others it is legal.

See Also[edit | edit source]

References[edit | edit source]


JWH-130 Resources
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Contributors: Prab R. Tumpati, MD