JWH-150
JWH-150 is a synthetic cannabinoid from the naphthoylindole family, which acts as a full agonist at both the CB1 and CB2 cannabinoid receptors, but with moderate selectivity for CB2. It was discovered by and named after Dr. John W. Huffman.
Chemistry[edit | edit source]
JWH-150 is part of the Naphthoylindole family of synthetic cannabinoids. It is structurally related to other synthetic cannabinoids including JWH-018, JWH-073, and JWH-200.
Pharmacology[edit | edit source]
JWH-150 acts as a full agonist at the CB1 and CB2 cannabinoid receptors. It has moderate selectivity for CB2, with a binding affinity of 39nM at CB1 and 12nM at CB2.
Legality[edit | edit source]
In the United States, all CB1 receptor agonists of the 3-(1-naphthoyl)indole class such as JWH-150 are Schedule I Controlled Substances.
See also[edit | edit source]
References[edit | edit source]
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