JWH-364

JWH-364

0JWH-364 is a synthetic cannabinoid from the naphthoylindole family, which acts as a potent and selective CB2 receptor agonist. It is part of the larger JWH series of compounds, named after the initials of the scientist who first synthesized them, John W. Huffman.

Chemistry

JWH-364 is a member of the naphthoylindole family of synthetic cannabinoids. It is structurally related to other synthetic cannabinoids in the JWH series, such as JWH-018 and JWH-073, but differs in the nature of its substituents. The chemical structure of JWH-364 includes a naphthoyl group, an indole ring, and a lipophilic alkyl chain.

Pharmacology

JWH-364 acts as a potent and selective agonist for the CB2 receptor, one of the two main types of cannabinoid receptors in the body. The CB2 receptor is primarily found in the immune system and is less prevalent in the brain than the CB1 receptor. Agonists of the CB2 receptor, such as JWH-364, can produce anti-inflammatory and analgesic effects.

Effects

The effects of JWH-364 are not well-studied in humans. However, based on its pharmacological profile, it is likely to produce effects similar to those of other CB2 receptor agonists. These may include anti-inflammatory and analgesic effects, as well as potential immunomodulatory effects. As a synthetic cannabinoid, JWH-364 may also produce psychoactive effects, although these are likely to be less pronounced than those of CB1 receptor agonists.

Legal Status

The legal status of JWH-364 varies by country. In many jurisdictions, it is considered a controlled substance due to its structural and pharmacological similarity to other synthetic cannabinoids. However, the specific legal status of JWH-364 should be verified for each individual jurisdiction.

See Also

• JWH series
• Synthetic cannabinoids
• CB2 receptor