JWH-370

JWH-370

0JWH-370 is a synthetic cannabinoid from the JWH series. It was developed by the team of John W. Huffman at Clemson University. It is a research chemical that acts as a potent agonist for the cannabinoid receptors.

History

The JWH series was developed in the mid-1990s by Huffman and his team in an effort to create a new class of cannabinoids. JWH-370 is one of the many compounds in this series. The exact date of its synthesis is not known, but it is believed to have been created in the late 1990s or early 2000s.

Chemistry

JWH-370 is a synthetic cannabinoid, meaning it is not naturally occurring but is instead created in a laboratory. It is a member of the naphthoylindole family of compounds. The chemical structure of JWH-370 includes a naphthalene ring, an indole ring, and a pentyl chain.

Pharmacology

JWH-370 acts as a potent agonist for the cannabinoid receptors, specifically the CB1 receptor and CB2 receptor. This means it binds to these receptors and activates them, producing effects similar to those of cannabis. However, as a synthetic cannabinoid, JWH-370 is often more potent than natural cannabis and can produce more intense and unpredictable effects.

Legal Status

The legal status of JWH-370 varies by country. In many places, it is considered a controlled substance due to its potential for abuse and the health risks associated with its use. However, as a research chemical, it may be legally obtained for scientific or medical research under certain conditions.

Health Risks

The health risks associated with JWH-370 are not fully understood, as it has not been extensively studied in humans. However, it is known that synthetic cannabinoids in general can have serious side effects, including psychosis, seizures, and even death. Therefore, use of JWH-370 is considered risky and is not recommended.

See Also

• JWH series
• Synthetic cannabinoids
• Cannabinoid receptors

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