Jasmonic acid

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Jasmonic acid is an organic compound that plays a crucial role in plant growth, development, and defense mechanisms. It is a type of plant hormone, specifically a member of the jasmonate family, which includes several related compounds such as methyl jasmonate. Jasmonic acid is involved in various plant processes, including seed germination, root growth, fruit ripening, and the response to environmental stresses such as wounding and pathogen attack.

The biosynthesis of jasmonic acid begins with the oxidation of alpha-linolenic acid, a fatty acid found in chloroplast membranes. This process involves several steps, including the action of the enzyme lipoxygenase, leading to the production of 12-oxo-phytodienoic acid (OPDA), which is then cyclized and reduced to form jasmonic acid. This pathway is known as the octadecanoid pathway.

Jasmonic acid exerts its effects by binding to specific receptors in the plant cell, initiating a signal transduction pathway that leads to the activation of gene expression related to plant defense and development. One of the key components of this signaling pathway is the JASMONATE ZIM-domain (JAZ) proteins, which repress transcription factors involved in jasmonate responses. Upon jasmonic acid binding, JAZ proteins are degraded, allowing the transcription factors to activate gene expression.

In addition to its role in plant defense against herbivores and pathogens, jasmonic acid is also involved in the regulation of plant growth and development. It affects processes such as flowering, senescence (aging), and stomatal closure. However, the action of jasmonic acid is often balanced by other plant hormones, such as auxins, gibberellins, and abscisic acid, highlighting the complex network of hormonal interactions that regulate plant physiology.

Jasmonic acid and its derivatives have been studied for their potential applications in agriculture. Due to their role in plant defense, they have been considered as agents for enhancing crop resistance to pests and diseases. However, the practical application of jasmonic acid in agriculture requires careful management to avoid adverse effects on plant growth and development.

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Contributors: Prab R. Tumpati, MD