Juxtacapillary receptors

Juxtacapillary receptors (also known as J-receptors or C-fiber receptors) are a type of pulmonary stretch receptors found in the lung. They are located in the alveolar walls close to the capillaries and are particularly sensitive to increases in the capillary pressure.

Function

Juxtacapillary receptors are sensitive to various factors such as pulmonary edema, pulmonary embolism, and congestive heart failure. They are activated by substances like bradykinin, serotonin, and prostaglandins that may accumulate in the lung interstitium. When activated, these receptors can trigger rapid, shallow breathing, sensations of dyspnea (shortness of breath), and coughing.

Structure

Juxtacapillary receptors are unmyelinated nerve fibers that are in close proximity to the capillaries in the alveolar wall. They are believed to be part of the non-myelinated C fibers of the vagus nerve.

Clinical significance

Understanding the function of juxtacapillary receptors can be crucial in managing conditions such as pulmonary edema and congestive heart failure. Their activation can be a sign of increased capillary pressure and can help in early detection and treatment of these conditions.

See also

• Pulmonary stretch receptors
• Vagus nerve
• Pulmonary edema
• Congestive heart failure