KCNE3
KCNE3 is a gene that in humans encodes the voltage-gated potassium channel subunit. This gene is also known as MinK-related peptide 2 (MiRP2) and potassium voltage-gated channel subfamily E regulatory subunit 3. The protein encoded by this gene is a member of the KCNE family of potassium channel genes and plays a crucial role in the function of the heart and the nervous system.
Function[edit | edit source]
The KCNE3 gene provides instructions for making a protein that works with other proteins to form potassium channels. These channels, which transport positively charged potassium ions across cell membranes, play a key role in a cell's ability to generate and transmit electrical signals.
Clinical significance[edit | edit source]
Mutations in the KCNE3 gene have been associated with certain medical conditions. For example, they have been linked to Brugada syndrome, a disorder that causes a disruption of the heart's normal rhythm. Additionally, mutations in this gene have been associated with hypokalemic periodic paralysis, a condition that causes episodes of muscle weakness or paralysis.
See also[edit | edit source]
References[edit | edit source]
External links[edit | edit source]
KCNE3 Resources | |
---|---|
|
Search WikiMD
Ad.Tired of being Overweight? Try W8MD's physician weight loss program.
Semaglutide (Ozempic / Wegovy and Tirzepatide (Mounjaro / Zepbound) available.
Advertise on WikiMD
WikiMD's Wellness Encyclopedia |
Let Food Be Thy Medicine Medicine Thy Food - Hippocrates |
Translate this page: - East Asian
中文,
日本,
한국어,
South Asian
हिन्दी,
தமிழ்,
తెలుగు,
Urdu,
ಕನ್ನಡ,
Southeast Asian
Indonesian,
Vietnamese,
Thai,
မြန်မာဘာသာ,
বাংলা
European
español,
Deutsch,
français,
Greek,
português do Brasil,
polski,
română,
русский,
Nederlands,
norsk,
svenska,
suomi,
Italian
Middle Eastern & African
عربى,
Turkish,
Persian,
Hebrew,
Afrikaans,
isiZulu,
Kiswahili,
Other
Bulgarian,
Hungarian,
Czech,
Swedish,
മലയാളം,
मराठी,
ਪੰਜਾਬੀ,
ગુજરાતી,
Portuguese,
Ukrainian
WikiMD is not a substitute for professional medical advice. See full disclaimer.
Credits:Most images are courtesy of Wikimedia commons, and templates Wikipedia, licensed under CC BY SA or similar.
Contributors: Prab R. Tumpati, MD