Ki Database

From WikiMD's Food, Medicine & Wellness Encyclopedia

Ki Database is a comprehensive database that contains information about the binding affinity of drugs and other chemical substances to various protein targets in the body. The database is an essential tool for pharmacology and drug discovery research, as it provides valuable insights into the interactions between drugs and their targets.

Overview[edit | edit source]

The Ki Database is a collection of data on the binding affinity, or Ki, of drugs and other chemical substances to various protein targets. The Ki value is a measure of how strongly a substance binds to a protein, and is a key parameter in pharmacology and drug discovery. The database contains data on thousands of substances and their targets, and is regularly updated with new data from scientific research.

Use in Pharmacology[edit | edit source]

In pharmacology, the Ki Database is used to study the interactions between drugs and their targets. By analyzing the Ki values of different substances, researchers can gain insights into how drugs interact with their targets, and how these interactions affect the drug's efficacy and side effects. This information can be used to design more effective and safer drugs.

Use in Drug Discovery[edit | edit source]

In drug discovery, the Ki Database is used to identify potential new drug targets. By analyzing the Ki values of different substances, researchers can identify proteins that are strongly bound by certain substances. These proteins can then be investigated as potential targets for new drugs.

Accessing the Ki Database[edit | edit source]

The Ki Database is freely accessible online, and can be searched by substance name, protein target, or Ki value. The database also provides tools for analyzing and visualizing the data, making it a valuable resource for researchers in pharmacology and drug discovery.

See Also[edit | edit source]

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Contributors: Prab R. Tumpati, MD