Knock in

From WikiMD's Food, Medicine & Wellness Encyclopedia

Knock in - replacement of a gene by an altered version of the same gene using homologous recombination resulting in a gain of function. One example of a knock in is deletion of a coding sequence of a gene in a mouse and then replacing it with human coding sequences.

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Clinical trials

Source: Data courtesy of the U.S. National Library of Medicine. Since the data might have changed, please query MeSH on Knock in for any updates.



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Contributors: Prab R. Tumpati, MD