Krause's glands
Krause's glands are a type of exocrine gland found in various locations in the body, most notably in the conjunctiva of the eye and the mucous membrane of the mouth. Named after the German anatomist Wilhelm Krause, these glands play a crucial role in maintaining the health and functionality of the tissues where they are located.
Function[edit | edit source]
Krause's glands are responsible for the production and secretion of a serous fluid that helps to keep the conjunctiva and oral mucosa moist. This fluid also contains various antibodies and antimicrobial peptides that help to protect these tissues from infection.
Anatomy[edit | edit source]
Krause's glands are typically small and round, with a diameter of about 1 millimeter. They are composed of a cluster of secretory acini that are surrounded by a thin layer of connective tissue. The acini are lined with epithelial cells that produce the gland's secretory product.
Clinical significance[edit | edit source]
Dysfunction or disease of Krause's glands can lead to a variety of clinical conditions. For example, dry eye syndrome can occur if the glands do not produce enough fluid to keep the conjunctiva moist. Conversely, overproduction of fluid can lead to excessive tearing or sialorrhea. Infections or tumors of Krause's glands are rare but can also cause significant morbidity.
See also[edit | edit source]
References[edit | edit source]
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Contributors: Prab R. Tumpati, MD