LDL
LDL or Low-Density Lipoprotein is a type of lipoprotein that is often referred to as "bad cholesterol". It is one of the five major groups of lipoproteins, which, in order of sizes, largest to smallest, are chylomicrons, VLDL, IDL, LDL, and HDL, that enable fats and cholesterol to move within the water-based solution of the bloodstream.
Structure[edit | edit source]
LDL particles are formed as VLDL lipoproteins lose triglyceride through the action of lipoprotein lipase (LPL) and they become smaller and denser (i.e., fewer fat molecules with same protein), containing a higher proportion of cholesterol esters.
Function[edit | edit source]
The primary role of LDL is to transport fats (lipids) around the body. While LDL is necessary for the body function, a high amount of LDL can lead to plaque formation in the arteries, which can increase the risk of heart disease and stroke.
Health Risks[edit | edit source]
High levels of LDL cholesterol can lead to atherosclerosis, heart disease, and stroke. It is therefore important to maintain a healthy balance of cholesterol in the body.
See Also[edit | edit source]
References[edit | edit source]
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Contributors: Prab R. Tumpati, MD
