LG-105

From WikiMD's Wellness Encyclopedia


LG-105 is a synthetic compound that has been studied for its potential use as a selective androgen receptor modulator (SARM). SARMs are a class of therapeutic compounds that have similar properties to anabolic agents, but with reduced androgenic (producing male characteristics) properties. This makes them potentially useful for treating conditions such as muscle wasting and osteoporosis without the side effects associated with traditional anabolic steroids.

Mechanism of Action[edit | edit source]

LG-105 works by selectively binding to androgen receptors in the body. Androgen receptors are a type of nuclear receptor that are activated by binding to androgenic hormones, such as testosterone. Once activated, these receptors regulate the expression of specific genes that control the development and maintenance of male characteristics and muscle mass.

Unlike traditional anabolic steroids, which can activate androgen receptors throughout the body, LG-105 is designed to selectively target receptors in muscle and bone tissue. This selective action is intended to promote muscle growth and bone density while minimizing effects on other tissues, such as the prostate and skin.

Potential Applications[edit | edit source]

The selective action of LG-105 makes it a promising candidate for several medical applications:

  • Muscle Wasting Diseases: LG-105 could be used to treat muscle wasting conditions, such as those associated with cancer, chronic illness, or aging.
  • Osteoporosis: By promoting bone density, LG-105 may help in the treatment of osteoporosis, a condition characterized by weak and brittle bones.
  • Hypogonadism: LG-105 might be used to treat hypogonadism, a condition where the body does not produce enough testosterone.

Research and Development[edit | edit source]

As of the latest updates, LG-105 is still under investigation in preclinical or early clinical trials. The safety, efficacy, and pharmacokinetics of LG-105 are being studied to determine its potential as a therapeutic agent.

Side Effects and Safety[edit | edit source]

While SARMs like LG-105 are designed to minimize side effects, potential adverse effects may still occur. These could include hormonal imbalances, liver toxicity, and cardiovascular issues. Long-term safety data is not yet available, and further research is needed to fully understand the risk profile of LG-105.

Regulatory Status[edit | edit source]

LG-105 is not currently approved for medical use by any major regulatory agency. It is considered an investigational compound and is primarily used in research settings.

Also see[edit | edit source]

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Contributors: Prab R. Tumpati, MD