LPAR4
LPAR4 or Lysophosphatidic Acid Receptor 4 is a protein that in humans is encoded by the LPAR4 gene. It is a member of the G protein-coupled receptor family and plays a significant role in various biological processes.
Function[edit | edit source]
LPAR4 is one of the several different receptors for lysophosphatidic acid (LPA), a phospholipid derivative extracellular signaling molecule. LPA receptors influence numerous physiological and pathological processes, including cell proliferation, cell differentiation, and apoptosis.
Gene[edit | edit source]
The LPAR4 gene is located on the chromosome 19 at position 13.2 and spans approximately 20,000 base pairs. The gene is composed of 2 exons and encodes a 365 amino acid protein.
Clinical Significance[edit | edit source]
Alterations in LPAR4 have been implicated in several diseases, including cancer, fibrosis, and inflammation. It has been suggested that LPAR4 could be a potential therapeutic target for these diseases.
See Also[edit | edit source]
References[edit | edit source]
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