Lanatoside C

Lanatoside C

Lanatoside C is a cardiac glycoside, a type of compound that has the ability to increase the force of contraction of the heart muscle while decreasing its rate of contractions. It is derived from the foxglove plant (Digitalis lanata) and is used in the treatment of certain heart conditions.

History

Lanatoside C was first isolated from the woolly foxglove plant in the early 20th century. Its therapeutic potential was recognized due to its similarity to digoxin, another cardiac glycoside that was already in use at the time.

Pharmacology

Lanatoside C works by inhibiting the sodium-potassium ATPase pump in the membranes of heart cells. This leads to an increase in the concentration of intracellular calcium ions, which in turn increases the force of heart muscle contractions. At the same time, lanatoside C decreases the rate of contractions, allowing the heart to rest between beats.

Clinical Use

Lanatoside C is used in the treatment of congestive heart failure and certain types of arrhythmia. It is usually administered orally, but can also be given by injection in emergency situations.

Side Effects

Like other cardiac glycosides, lanatoside C can have serious side effects if used improperly. These can include nausea, vomiting, diarrhea, blurred vision, and hallucinations. In severe cases, it can cause life-threatening arrhythmia.

See Also

• Cardiac glycoside
• Digoxin
• Sodium-potassium ATPase
• Congestive heart failure
• Arrhythmia