Lapisteride

Lapisteride is a pharmaceutical drug used in the treatment of benign prostatic hyperplasia (BPH) and androgenetic alopecia (male pattern baldness). It is a 5α-reductase inhibitor, a class of drugs that inhibit the conversion of testosterone to dihydrotestosterone (DHT).

Mechanism of Action

Lapisteride works by inhibiting the enzyme 5α-reductase, which is responsible for the conversion of testosterone to DHT. DHT is a potent androgen that stimulates the growth of prostate cells and hair follicles. By reducing the levels of DHT, lapisteride can help to shrink an enlarged prostate and slow down or stop hair loss.

Uses

Benign Prostatic Hyperplasia

Lapisteride is used in the treatment of BPH, a common condition in older men where the prostate gland becomes enlarged. This can cause problems with urination, such as a weak stream or the need to urinate frequently. By reducing the size of the prostate, lapisteride can help to alleviate these symptoms.

Androgenetic Alopecia

Lapisteride is also used to treat androgenetic alopecia, a common form of hair loss in men. By inhibiting the action of DHT on hair follicles, lapisteride can help to slow down or stop hair loss and in some cases, promote hair regrowth.

Side Effects

Like all drugs, lapisteride can cause side effects. These may include decreased libido, erectile dysfunction, and ejaculation disorders. In rare cases, it can also cause breast enlargement and tenderness.

See Also

• 5α-reductase inhibitor
• Benign prostatic hyperplasia
• Androgenetic alopecia

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