Ledol

Ledol is a toxic substance found in the plant species Rhododendron tomentosum, commonly known as marsh Labrador tea. It is a sesquiterpene that is structurally similar to thujone, another plant-based toxin. Ledol is known for its strong, unpleasant smell and its potential to cause poisoning in humans and animals.

Chemical Structure and Properties

Ledol is a sesquiterpene, a class of terpenes that consists of three isoprene units and has the molecular formula C15H24. It is structurally similar to thujone, a toxin found in several plant species including wormwood (Artemisia absinthium). Ledol has a strong, unpleasant smell that is often described as turpentine-like.

Sources

The primary source of ledol is the plant Rhododendron tomentosum, also known as marsh Labrador tea. This plant is native to the northern regions of North America, Europe, and Asia, and is particularly common in bogs and other wetland habitats. Other species of Rhododendron may also contain ledol, although in smaller amounts.

Toxicity

Ledol is a potent toxin. When ingested, it can cause a range of symptoms including nausea, vomiting, abdominal pain, and in severe cases, seizures and death. The toxin is also absorbed through the skin, making it dangerous to handle plants containing ledol without proper protection. Animals that consume plants containing ledol, such as sheep and cattle, can also suffer from poisoning.

Treatment and Prevention

Treatment for ledol poisoning is primarily supportive, with the aim of managing symptoms and preventing further absorption of the toxin. This may include inducing vomiting, administering activated charcoal to bind the toxin in the stomach, and providing supportive care such as fluids and electrolytes. Prevention of ledol poisoning involves avoiding contact with and ingestion of plants containing the toxin.

See Also

• Rhododendron tomentosum
• Sesquiterpene
• Thujone
• Terpenes

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