Leukocyte disorders

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Leukocyte Disorders are a group of disorders that affect the white blood cells (leukocytes) in the human body. These disorders can be either congenital or acquired and can lead to a variety of health problems, including increased susceptibility to infections, autoimmune diseases, and malignancies.

Types of Leukocyte Disorders[edit | edit source]

There are several types of leukocyte disorders, each affecting a different type of white blood cell. These include:

  • Neutrophil Disorders: These disorders affect the neutrophils, the most common type of white blood cell. They include conditions such as neutropenia, which is characterized by a low neutrophil count, and neutrophilia, which is characterized by a high neutrophil count.
  • Lymphocyte Disorders: These disorders affect the lymphocytes, a type of white blood cell that plays a key role in the immune response. They include conditions such as lymphocytosis, which is characterized by a high lymphocyte count, and lymphocytopenia, which is characterized by a low lymphocyte count.
  • Monocyte Disorders: These disorders affect the monocytes, a type of white blood cell that plays a role in the immune response and inflammation. They include conditions such as monocytosis, which is characterized by a high monocyte count, and monocytopenia, which is characterized by a low monocyte count.

Causes of Leukocyte Disorders[edit | edit source]

Leukocyte disorders can be caused by a variety of factors, including genetic mutations, infections, autoimmune diseases, and certain medications. In some cases, the cause of the disorder is unknown.

Diagnosis and Treatment[edit | edit source]

Diagnosis of leukocyte disorders typically involves blood tests to measure the number and type of white blood cells. Additional tests may be needed to determine the underlying cause of the disorder.

Treatment for leukocyte disorders depends on the type and severity of the disorder, as well as the underlying cause. It may include medications to boost the immune system, antibiotics to treat infections, or in severe cases, a bone marrow transplant.

See Also[edit | edit source]


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Contributors: Prab R. Tumpati, MD