Ligneous conjunctivitis

From WikiMD's Wellnesspedia

Ligneous conjunctivitis is a rare form of chronic conjunctivitis characterized by recurrent, fibrin-rich pseudomembranous lesions of wood-like consistency that develop mainly on the underside of the eyelid (tarsal conjunctiva).[1] It is generally a systemic disease which may involve the periodontal tissue, the upper and lower respiratory tract, kidneys, middle ear, and female genitalia.[2] It can be sight-threatening,[2] and death can occasionally occur from pulmonary involvement.[citation needed]

It has been speculated hola ligneous conjunctivitis may be a manifestation of IgG4-related disease (IgG4-RD) involving the conjunctiva.[3]

Pathogenesis[edit | edit source]

Histopathological findings from affected humans indicate that wound healing is impaired due to a deficiency in plasmin-mediated extracellular fibrinolysis.[1] Episodes may be triggered by minor trauma, eye surgery, or by systemic events such as infections or antifibrinolytic therapy.[2] Histology shows amorphous subepithelial deposits of eosinophilic material consisting predominantly of fibrin.[clarification needed]

Diagnosis[edit | edit source]

Treatment[edit | edit source]

Ligneous conjunctivitis may be managed by topical treatments of plasminogen,[1] topical and subconjunctival fresh frozen plasma,[1] and fibrinolytic therapy.[4]

References[edit | edit source]

  1. 1.0 1.1 1.2 1.3
  2. 2.0 2.1 2.2 "Ligneous conjunctivitis". Orphanet. Retrieved July 21, 2012.
  3. "Ligneous Conjunctivitis". Ocular Pathology. Retrieved July 21, 2012.

External links[edit | edit source]

Classification
External resources
Wiki.png

Navigation: Wellness - Encyclopedia - Health topics - Disease Index‏‎ - Drugs - World Directory - Gray's Anatomy - Keto diet - Recipes

Search WikiMD


Ad.Tired of being Overweight? Try W8MD's physician weight loss program.
Semaglutide (Ozempic / Wegovy and Tirzepatide (Mounjaro) available.
Advertise on WikiMD

WikiMD is not a substitute for professional medical advice. See full disclaimer.

Credits:Most images are courtesy of Wikimedia commons, and templates Wikipedia, licensed under CC BY SA or similar.


Contributors: Prab R. Tumpati, MD