Ligneous conjunctivitis
| Ligneous conjunctivitis | |
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| Synonyms | Conjunctivitis lignosa[1] |
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| Field | ophthalmology |
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Ligneous conjunctivitis is a rare form of chronic conjunctivitis characterized by recurrent, fibrin-rich pseudomembranous lesions of wood-like consistency that develop mainly on the underside of the eyelid (tarsal conjunctiva).[2] It is generally a systemic disease which may involve the periodontal tissue, the upper and lower respiratory tract, kidneys, middle ear, and female genitalia.[3] It can be sight-threatening,[3] and death can occasionally occur from pulmonary involvement.
(July 2012)
It has been speculated hola ligneous conjunctivitis may be a manifestation of IgG4-related disease (IgG4-RD) involving the conjunctiva.[4]
Pathogenesis[edit | edit source]
Histopathological findings from affected humans indicate that wound healing is impaired due to a deficiency in plasmin-mediated extracellular fibrinolysis.[2] Episodes may be triggered by minor trauma, eye surgery, or by systemic events such as infections or antifibrinolytic therapy.[3] Histology shows amorphous subepithelial deposits of eosinophilic material consisting predominantly of fibrin. [clarification needed]
Diagnosis[edit | edit source]
![[icon]](/wiki/File:Wiki_letter_w_cropped.svg){kind=small} | This section is empty. You can help by adding to it. (December 2017) |
Treatment[edit | edit source]
Ligneous conjunctivitis may be managed by topical treatments of plasminogen,[2] topical and subconjunctival fresh frozen plasma,[2] and fibrinolytic therapy.[5]
References[edit | edit source]
- ↑ Orphanet: Ligneous conjunctivitis Full text, www.orpha.net,
- ↑ 2.0 2.1 2.2 2.3 , Ligneous conjunctivitis, Survey of Ophthalmology, 2003, Vol. 48(Issue: 4), pp. 369–388, DOI: 10.1016/s0039-6257(03)00056-0, PMID: 12850227,
- ↑ 3.0 3.1 3.2 Ligneous conjunctivitis Full text, , Orphanet,
- ↑ , Co-existing ligneous conjunctivitis and IgG4-related disease, Indian Journal of Ophthalmology, Vol. 64(Issue: 7), pp. 532–534, DOI: 10.4103/0301-4738.190154, PMID: 27609168, PMC: 5026081, Full text,
- ↑ Ligneous Conjunctivitis Full text, , Ocular Pathology,
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