Linolelaidic acid

From WikiMD's Food, Medicine & Wellness Encyclopedia

Linolelaidic acid is a trans fatty acid that is a geometric isomer of linoleic acid, a polyunsaturated omega-6 fatty acid. It is found in partially hydrogenated vegetable oils and is associated with an increased risk of various health issues, including heart disease and inflammation. Linolelaidic acid is one of the many trans fats that have been the subject of health-related research and regulatory action due to their negative effects on human health.

Structure and Properties[edit | edit source]

Linolelaidic acid has the chemical formula C18H32O2 and is characterized by its trans configuration of the carbon-carbon double bonds. This structural difference from linoleic acid, which has cis double bonds, affects the physical and biological properties of the fatty acid. The trans configuration of linolelaidic acid results in a more linear structure, which allows it to pack more closely in cell membranes and affects the fluidity of the membranes.

Sources[edit | edit source]

Linolelaidic acid is not typically found in large amounts in natural food sources. Its presence in the human diet is primarily due to the industrial processing of vegetable oils. During the process of partial hydrogenation, which is used to increase the shelf life and stability of vegetable oils, trans fats like linolelaidic acid are formed. Foods that may contain linolelaidic acid include margarine, shortening, fried foods, and many commercially baked goods.

Health Effects[edit | edit source]

The consumption of trans fats, including linolelaidic acid, has been linked to an increased risk of several health conditions. These include coronary heart disease, as trans fats contribute to the buildup of plaque in the arteries, leading to atherosclerosis. Additionally, linolelaidic acid may play a role in promoting inflammation, insulin resistance, and obesity, further exacerbating the risk of cardiovascular disease and type 2 diabetes.

Regulation and Recommendations[edit | edit source]

Due to the adverse health effects associated with trans fats, many health organizations and governmental bodies have issued guidelines and regulations to limit their consumption. The World Health Organization (WHO) recommends that trans fat intake be limited to less than 1% of total energy intake. In response, some countries have implemented mandatory labeling of trans fats on food products, and others have taken steps to reduce or eliminate industrially produced trans fats from the food supply.

Conclusion[edit | edit source]

Linolelaidic acid is a trans fatty acid with significant implications for human health. Its presence in the diet, primarily through processed foods, has been linked to an increased risk of heart disease and other health conditions. Efforts to reduce the consumption of trans fats, including linolelaidic acid, are important for improving public health outcomes.


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Contributors: Prab R. Tumpati, MD