Linsidomine
Linsidomine is a vasodilator and a nitric oxide donor. It is used in the treatment of erectile dysfunction and anal fissures.
Mechanism of Action[edit | edit source]
Linsidomine works by releasing nitric oxide, which then activates the enzyme guanylate cyclase. This enzyme increases the levels of cyclic guanosine monophosphate (cGMP), leading to smooth muscle relaxation in the corpus cavernosum, resulting in increased blood flow and an erection.
Uses[edit | edit source]
Linsidomine is used in the treatment of erectile dysfunction and anal fissures. It is applied topically in the form of a cream or ointment.
Erectile Dysfunction[edit | edit source]
In the treatment of erectile dysfunction, linsidomine is applied topically to the penis. The nitric oxide released by the drug causes the smooth muscles in the corpus cavernosum to relax, allowing for increased blood flow and an erection.
Anal Fissures[edit | edit source]
Linsidomine is also used in the treatment of anal fissures. It is applied topically to the anus, where it causes the smooth muscles in the anal sphincter to relax, reducing pain and promoting healing.
Side Effects[edit | edit source]
Common side effects of linsidomine include headache, dizziness, and flushing. Less common side effects include hypotension, tachycardia, and syncope.
See Also[edit | edit source]
| Linsidomine Resources | |
|---|---|
|
 |
Search WikiMD
Ad.Tired of being Overweight? Try W8MD's physician weight loss program.
Semaglutide (Ozempic / Wegovy and Tirzepatide (Mounjaro / Zepbound) available.
Advertise on WikiMD
|
WikiMD's Wellness Encyclopedia |
| Let Food Be Thy Medicine Medicine Thy Food - Hippocrates |
Translate this page: - East Asian
中文,
日本,
한국어,
South Asian
हिन्दी,
தமிழ்,
తెలుగు,
Urdu,
ಕನ್ನಡ,
Southeast Asian
Indonesian,
Vietnamese,
Thai,
မြန်မာဘာသာ,
বাংলা
European
español,
Deutsch,
français,
Greek,
português do Brasil,
polski,
română,
русский,
Nederlands,
norsk,
svenska,
suomi,
Italian
Middle Eastern & African
عربى,
Turkish,
Persian,
Hebrew,
Afrikaans,
isiZulu,
Kiswahili,
Other
Bulgarian,
Hungarian,
Czech,
Swedish,
മലയാളം,
मराठी,
ਪੰਜਾਬੀ,
ગુજરાતી,
Portuguese,
Ukrainian
Medical Disclaimer: WikiMD is not a substitute for professional medical advice. The information on WikiMD is provided as an information resource only, may be incorrect, outdated or misleading, and is not to be used or relied on for any diagnostic or treatment purposes. Please consult your health care provider before making any healthcare decisions or for guidance about a specific medical condition. WikiMD expressly disclaims responsibility, and shall have no liability, for any damages, loss, injury, or liability whatsoever suffered as a result of your reliance on the information contained in this site. By visiting this site you agree to the foregoing terms and conditions, which may from time to time be changed or supplemented by WikiMD. If you do not agree to the foregoing terms and conditions, you should not enter or use this site. See full disclaimer.
Credits:Most images are courtesy of Wikimedia commons, and templates Wikipedia, licensed under CC BY SA or similar.
Contributors: Prab R. Tumpati, MD
