List of EORTC trials

List of EORTC Trials

The European Organisation for Research and Treatment of Cancer (EORTC) is a non-profit international cancer research organisation that conducts clinical trials to investigate the efficacy of various cancer treatments. EORTC trials are pivotal in advancing cancer research, offering insights into the best practices for cancer care, and improving patient outcomes. This article provides an overview of notable EORTC trials, highlighting their significance in the field of oncology.

Overview

The EORTC was established with the aim of conducting, developing, coordinating, and stimulating laboratory and clinical research in Europe to improve the management of cancer and related problems by increasing survival and improving the quality of life for patients. The organisation plays a crucial role in facilitating the transition of experimental discoveries into state-of-the-art treatment. EORTC trials cover various types of cancer, including but not limited to breast, lung, prostate, and melanoma.

Notable EORTC Trials

Below is an incomplete list of significant EORTC trials that have contributed to the understanding and treatment of cancer. This list is not exhaustive and serves as a starting point for exploring the extensive work done by the EORTC.

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• EORTC 10853 - A trial focused on breast cancer, specifically investigating the role of breast-conserving therapy versus mastectomy in patients with early-stage disease.
• EORTC 22921 - A study in rectal cancer patients, examining the effects of preoperative radiotherapy combined with or without chemotherapy.
• EORTC 26981 - A trial that explored the efficacy of radiotherapy plus concomitant and adjuvant temozolomide for glioblastoma.
• EORTC 40983 - This trial aimed to assess the impact of perioperative chemotherapy on resectable liver metastases from colorectal cancer.
• EORTC 62012 - A study focusing on the treatment of high-risk soft tissue sarcoma with chemotherapy.
• EORTC 62931 - This trial investigated the role of chemotherapy in patients with operable soft tissue sarcoma after surgical resection.

Impact of EORTC Trials

EORTC trials have significantly contributed to the advancement of cancer treatment protocols and strategies. By rigorously testing new treatments and comparing them to current standards, these trials help in identifying more effective therapies and approaches for cancer care. The findings from EORTC trials have led to changes in clinical practice and have been instrumental in improving survival rates and quality of life for cancer patients worldwide.

Future Directions

The EORTC continues to pioneer in the field of cancer research, with ongoing trials focusing on a wide range of cancers and treatment modalities. Future trials will likely incorporate emerging technologies, such as precision medicine and immunotherapy, further enhancing the understanding and management of cancer.