List of conditions treated with hematopoietic stem cell transplantation

This article provides a comprehensive list of medical conditions that can be treated using hematopoietic stem cell transplantation (HSCT). HSCT is a procedure that involves the transplantation of hematopoietic stem cells, which are responsible for the production of blood cells, to replace damaged or diseased cells in the body. It is commonly used as a treatment option for various conditions, including:

Leukemia

Leukemia is a type of cancer that affects the blood and bone marrow. HSCT is often used as a curative treatment for leukemia, particularly in cases where chemotherapy or radiation therapy has not been successful. The procedure involves replacing the patient's diseased bone marrow with healthy stem cells to restore normal blood cell production.

Lymphoma

Lymphoma is a cancer that affects the lymphatic system, which is responsible for fighting infections. HSCT can be used as a treatment option for certain types of lymphoma, such as Hodgkin lymphoma and non-Hodgkin lymphoma. The transplantation of healthy stem cells helps to rebuild the immune system and fight against the cancer cells.

Multiple Myeloma

Multiple myeloma is a cancer that affects plasma cells, which are responsible for producing antibodies. HSCT can be used as a treatment option for multiple myeloma, particularly in cases where other treatments have not been successful. The procedure involves replacing the patient's diseased plasma cells with healthy stem cells to restore normal antibody production.

Aplastic Anemia

Aplastic anemia is a condition characterized by a decrease in the production of red blood cells, white blood cells, and platelets. HSCT can be used as a treatment option for severe cases of aplastic anemia, where other treatments have not been effective. The transplantation of healthy stem cells helps to restore normal blood cell production and improve the patient's overall health.

Sickle Cell Disease

Sickle cell disease is a genetic disorder that affects the shape and function of red blood cells. HSCT can be used as a curative treatment for sickle cell disease, particularly in children. The procedure involves replacing the patient's diseased red blood cells with healthy stem cells to restore normal blood cell function and prevent complications associated with the disease.

Thalassemia

Thalassemia is a genetic disorder that affects the production of hemoglobin, a protein responsible for carrying oxygen in the blood. HSCT can be used as a treatment option for severe cases of thalassemia, particularly in children. The transplantation of healthy stem cells helps to restore normal hemoglobin production and improve the patient's overall health.

Immunodeficiency disorders

Immunodeficiency disorders are conditions characterized by a weakened immune system, making individuals more susceptible to infections. HSCT can be used as a treatment option for certain types of immunodeficiency disorders, such as severe combined immunodeficiency (SCID) and Wiskott-Aldrich syndrome. The transplantation of healthy stem cells helps to rebuild the immune system and improve the patient's ability to fight against infections.

Inherited metabolic disorders

Inherited metabolic disorders are genetic conditions that affect the body's ability to break down and process certain substances. HSCT can be used as a treatment option for certain types of inherited metabolic disorders, such as Hurler syndrome and adrenoleukodystrophy. The transplantation of healthy stem cells helps to replace the defective cells and improve the patient's overall metabolic function.

Autoimmune diseases

Autoimmune diseases are conditions characterized by an overactive immune system that mistakenly attacks healthy cells and tissues in the body. HSCT can be used as a treatment option for certain types of autoimmune diseases, such as multiple sclerosis and systemic sclerosis. The transplantation of healthy stem cells helps to reset the immune system and reduce the autoimmune response.

Solid tumors

HSCT can also be used as a treatment option for certain types of solid tumors, such as neuroblastoma and germ cell tumors. The transplantation of healthy stem cells can help to destroy cancer cells and prevent the tumor from spreading.

See also

• Hematopoietic stem cell transplantation
• List of hematopoietic stem cell transplantation registries

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