List of side effects of buspirone

Buspirone is an anxiolytic medication, primarily used to treat generalized anxiety disorder (GAD). Unlike many other anxiolytics, buspirone does not exhibit the sedative and addictive properties commonly associated with benzodiazepines. Its mechanism of action is not fully understood, but it is known to affect serotonin and dopamine neurotransmitter systems. This article provides a detailed list of side effects associated with buspirone, categorized by their frequency and severity.

Common Side Effects

Common side effects of buspirone occur more frequently but are generally mild and tend to decrease as the body adjusts to the medication. These include:

• Dizziness
• Nausea
• Headache
• Excitement
• Nervousness
• Lightheadedness

Less Common Side Effects

Less common side effects are observed less frequently and can be more severe, requiring medical attention:

• Confusion
• Rash
• Insomnia
• Fatigue
• Weakness
• Blurred vision

Rare Side Effects

Rare side effects of buspirone are uncommon but can be serious. Immediate medical attention should be sought if these occur:

• Serotonin Syndrome - a potentially life-threatening condition characterized by high body temperature, agitation, increased reflexes, tremor, sweating, dilated pupils, and diarrhea.
• Angioedema - swelling of the deeper layers of the skin, often around the eyes and lips.
• Hallucinations

Very Rare Side Effects

Very rare side effects have been reported in a small number of cases. These include:

• Tardive Dyskinesia - a disorder that involves involuntary movements, especially of the lower face.
• Hepatitis - inflammation of the liver.

Frequency Not Known

For some side effects of buspirone, the frequency is not known. These include:

• Depression
• Muscle pain
• Tinnitus - ringing in the ears.

Withdrawal Symptoms

Although buspirone is not known to be addictive, discontinuing the medication abruptly can lead to withdrawal symptoms such as:

• Anxiety
• Irritability
• Nausea
• Dizziness

Precautions

Patients with a history of drug allergies, kidney disease, or liver disease should use buspirone with caution. It is also important to avoid consuming Alcohol while taking buspirone, as it can enhance the sedative effects of the medication.

Interactions

Buspirone can interact with other medications, leading to increased side effects or decreased effectiveness. Notable interactions include:

• Monoamine Oxidase Inhibitors (MAOIs)
• Selective Serotonin Reuptake Inhibitors (SSRIs)
• St. John's Wort

Conclusion

While buspirone is an effective treatment for anxiety with a relatively mild side effect profile compared to other anxiolytics, patients should be aware of the potential side effects and interactions. Regular consultation with a healthcare provider is essential to monitor the medication's effectiveness and manage any adverse effects. This list is incomplete; you can help WikiMD by expanding it.