List of side effects of doxepin

Doxepin is a medication primarily used to treat major depressive disorder, anxiety disorders, and chronic hives. It belongs to a class of drugs known as tricyclic antidepressants (TCAs). Like all medications, doxepin can cause side effects, some of which may be serious. This article provides a detailed list of side effects associated with doxepin, categorized by their frequency and severity.

Common Side Effects

Common side effects of doxepin include, but are not limited to:

• Drowsiness
• Dry mouth
• Blurred vision
• Dizziness
• Weight gain
• Constipation
• Nausea
• Urinary retention

These side effects are generally mild and often decrease in severity with continued use of the medication.

Less Common Side Effects

Less common side effects of doxepin may include:

• Tinnitus
• Confusion
• Disorientation
• Tachycardia (rapid heart rate)
• Orthostatic hypotension (a form of low blood pressure that happens when you stand up from sitting or lying down)
• Sexual dysfunction

Rare Side Effects

Rare, but more serious side effects of doxepin can include:

• Seizures
• Hepatitis
• Agranulocytosis (a severe drop in white blood cells)
• Leukopenia (a decrease in the total number of white blood cells)
• Neutropenia (a decrease in the number of neutrophils, a type of white blood cell)
• Pancytopenia (a reduction in the number of red and white blood cells, as well as platelets)

Severe Allergic Reactions

In rare cases, doxepin can cause severe allergic reactions, symptoms of which may include:

• Rash
• Itching
• Swelling (especially of the face, tongue, or throat)
• Severe dizziness
• Trouble breathing

If you experience any of these symptoms, seek medical attention immediately.

Long-term Side Effects

Long-term use of doxepin can lead to additional side effects, such as:

• Cataracts
• Bone density loss
• Memory impairment

Withdrawal Symptoms

Discontinuing doxepin abruptly can lead to withdrawal symptoms, including:

• Insomnia
• Headache
• Nausea
• Malaise

It is important to taper off doxepin under the guidance of a healthcare provider to minimize withdrawal symptoms.

Conclusion

While doxepin is an effective medication for treating certain conditions, it is important for patients to be aware of its potential side effects. If you experience any adverse effects while taking doxepin, consult your healthcare provider for advice.

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