Lithium orotate

Lithium orotate is a chemical compound consisting of lithium, a alkali metal, and orotic acid, a pyrimidine derivative. It is often used as a dietary supplement and is touted for its potential benefits in neurological and mental health conditions, although its efficacy and safety are not universally accepted.

Chemistry[edit | edit source]

Lithium orotate is a salt formed by the reaction of lithium and orotic acid. The lithium ion is bonded to the orotate ion, forming a stable compound. The orotate ion acts as a chelating agent, helping to transport the lithium ion across cell membranes.

Uses[edit | edit source]

Lithium orotate is primarily used as a dietary supplement. It is believed to have potential benefits in the treatment of various neurological and mental health conditions, including bipolar disorder, depression, and anxiety. However, the evidence supporting these claims is not robust and more research is needed to confirm these potential benefits.

Safety and Side Effects[edit | edit source]

The safety of lithium orotate is a subject of debate. Some studies suggest that it may have fewer side effects than other forms of lithium, but these findings are not universally accepted. Potential side effects include nausea, vomiting, diarrhea, and in severe cases, lithium toxicity. Long-term use of lithium orotate may also lead to kidney damage.

Regulation[edit | edit source]

In many countries, including the United States, lithium orotate is classified as a dietary supplement and is not regulated by the Food and Drug Administration (FDA). This means that it is not subject to the same rigorous testing and quality control standards as prescription and over-the-counter medications.