Locus Biosciences
Locus Biosciences is a biotechnology company that specializes in the development of CRISPR-Cas system-based bacteriophage therapies. The company was founded in 2015 and is headquartered in Research Triangle Park, North Carolina, United States.
Overview[edit | edit source]
Locus Biosciences is a leader in the field of CRISPR-based bacteriophage therapeutics. The company's primary focus is on the development of precision antibacterial therapies that can combat antibiotic-resistant bacterial infections. Locus Biosciences uses a unique approach that combines bacteriophages with the CRISPR-Cas system to specifically target and kill pathogenic bacteria while leaving the beneficial bacteria unharmed.
Technology[edit | edit source]
The technology used by Locus Biosciences is based on the CRISPR-Cas3 system, which is different from the more commonly known CRISPR-Cas9 system. While the CRISPR-Cas9 system is used for gene editing, the CRISPR-Cas3 system is used by Locus Biosciences for its ability to cause DNA degradation in targeted bacteria, effectively killing them.
Products[edit | edit source]
Locus Biosciences is developing a pipeline of products that target various pathogenic bacteria. These include therapies for urinary tract infections, Clostridium difficile infections, and Pseudomonas aeruginosa infections, among others.
Partnerships[edit | edit source]
Locus Biosciences has entered into several strategic partnerships to advance its technology and product development. These include partnerships with Janssen Pharmaceuticals, a division of Johnson & Johnson, and the Bill & Melinda Gates Foundation.
See also[edit | edit source]
References[edit | edit source]
External links[edit | edit source]
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