Loteprednol/tobramycin

Loteprednol/Tobramycin is a combination medication used in the treatment of bacterial infections and inflammation in the eye. It contains two active ingredients: Loteprednol, a corticosteroid, and Tobramycin, an antibiotic.

Indications

Loteprednol/Tobramycin is indicated for the treatment of steroid-responsive inflammatory ocular conditions for which a corticosteroid is indicated and where bacterial infection or a risk of bacterial ocular infection exists. These conditions include conjunctivitis, keratitis, keratoconjunctivitis, corneal ulcers, blepharitis, blepharoconjunctivitis, acute meibomianitis, and dacryocystitis.

Mechanism of Action

Loteprednol works by reducing inflammation in the eye by inhibiting the release of substances in the body that cause inflammation. Tobramycin, on the other hand, works by stopping the growth of bacteria. It does this by binding to components of the bacterial cell leading to the inhibition of protein synthesis and thus bacterial growth.

Side Effects

Common side effects of Loteprednol/Tobramycin include blurred vision, eye discomfort, and sensitivity to light. More serious side effects may include eye pain, vision changes, and continued redness or irritation of the eye.

Contraindications

Loteprednol/Tobramycin is contraindicated in individuals with known or suspected hypersensitivity to any of the ingredients of this preparation and to other corticosteroids.

Drug Interactions

Loteprednol/Tobramycin may interact with other medications, including other eye medications. It is important to inform your healthcare provider about all other medications you are currently taking.

See Also

• Ophthalmic anti-infectives and anti-inflammatories
• Corticosteroids
• Antibiotics