Louise Pearce

Photograph of Louise Pearce (1885-1959) (cropped)

Louise Pearce (March 5, 1885 – August 10, 1959) was an American pathologist and physician renowned for her work in the treatment of African trypanosomiasis (sleeping sickness). She was one of the first women to graduate from the Johns Hopkins University School of Medicine and made significant contributions to medical research and public health.

Early Life and Education

Louise Pearce was born in Winchester, Massachusetts. She attended Stanford University, where she earned her undergraduate degree in 1907. She then pursued her medical degree at the Johns Hopkins University School of Medicine, graduating in 1912. Pearce was one of the few women in her class, reflecting the limited opportunities for women in medicine at the time.

Career and Research

After completing her medical degree, Pearce joined the Rockefeller Institute for Medical Research (now Rockefeller University) in 1913. She worked under the guidance of Simon Flexner, a prominent pathologist and bacteriologist.

African Trypanosomiasis

Pearce's most notable work was in the treatment of African trypanosomiasis, a disease caused by the Trypanosoma brucei parasite and transmitted by the tsetse fly. In collaboration with her colleagues, Pearce helped develop tryparsamide, an arsenical compound that proved effective in treating the disease. This breakthrough significantly reduced the mortality rate of sleeping sickness and was a major advancement in tropical medicine.

Other Contributions

In addition to her work on African trypanosomiasis, Pearce conducted research on syphilis and other infectious diseases. She published numerous papers in scientific journals and was recognized for her meticulous research and dedication to improving public health.

Personal Life and Legacy

Louise Pearce was known for her commitment to her work and her pioneering spirit. She was a member of several professional organizations, including the American Society for Microbiology and the American Association of Pathologists and Bacteriologists. Pearce's contributions to medicine were acknowledged with various awards and honors throughout her career.

Pearce passed away on August 10, 1959, leaving behind a legacy of scientific achievement and a trailblazing path for women in medicine.

See Also

• Pathology
• Johns Hopkins University School of Medicine
• Rockefeller University
• African trypanosomiasis
• Tryparsamide