Low molecular weight heparin

Low Molecular Weight Heparin (LMWH) is a class of anticoagulant medications. They are used as a treatment for blood clots and prevention of complications of pregnancy.

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Overview

LMWHs, including enoxaparin, dalteparin, and tinzaparin, are derived from unfractionated heparin. They have a lower molecular weight than unfractionated heparin, hence the name. LMWHs have a more predictable anticoagulant response, are easier to use, and have fewer side effects than unfractionated heparin.

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Fraxiparine 0,4 ml inj

Uses

LMWHs are used to prevent and treat deep vein thrombosis (DVT), pulmonary embolism (PE), and to prevent blood clots in the veins of patients who are on bed rest or who are having orthopedic surgery.

Mechanism of Action

LMWHs work by enhancing the activity of antithrombin III, an enzyme that inactivates thrombin and factor Xa, two key players in the coagulation cascade.

Side Effects

Common side effects of LMWHs include bleeding, bruising, and allergic reactions. In rare cases, LMWHs can cause heparin-induced thrombocytopenia (HIT), a serious condition where the body's immune system attacks its own platelets.

See Also

• Anticoagulant
• Deep vein thrombosis
• Pulmonary embolism
• Heparin-induced thrombocytopenia

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