Lymphangion

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Lymphangion is the functional unit of a lymphatic vessel that lies between two semilunar valves. The lymphangion propels lymph forward, preventing its backflow and ensuring its return to the bloodstream.

Structure[edit | edit source]

The lymphangion is composed of a segment of the lymphatic vessel that is bounded by two semilunar valves. These valves are responsible for preventing the backflow of lymph. The walls of the lymphangion contain smooth muscle fibers that contract rhythmically, propelling the lymph forward.

Function[edit | edit source]

The primary function of the lymphangion is to transport lymph back to the bloodstream. This is achieved through the rhythmic contraction and relaxation of the smooth muscle fibers in the lymphangion walls, a process known as lymphatic pumping.

The lymphangion also plays a crucial role in maintaining the body's fluid balance. It helps to return excess interstitial fluid and proteins that have leaked from the blood capillaries back to the bloodstream.

Clinical significance[edit | edit source]

Dysfunction of the lymphangion can lead to lymphedema, a condition characterized by swelling due to the accumulation of lymph in the tissues. This can occur as a result of damage to the lymphatic vessels or their valves, or due to a failure of the lymphatic pumping mechanism.

Lymphangion Resources
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Contributors: Prab R. Tumpati, MD