Lypressin
Lypressin is a synthetic form of vasopressin, a naturally occurring hormone in the body. It is used in the treatment of diabetes insipidus, a condition characterized by excessive thirst and the excretion of large amounts of urine. Lypressin works by reducing the amount of urine produced by the kidneys and helping the body retain water.
Mechanism of Action[edit | edit source]
Lypressin acts on the V2 receptors in the renal collecting ducts, leading to increased water reabsorption. This results in a decrease in urine volume and an increase in urine concentration. The drug also has a minor effect on the V1 receptor, which leads to vasoconstriction.
Uses[edit | edit source]
Lypressin is primarily used in the treatment of central diabetes insipidus, a condition caused by a deficiency of the hormone vasopressin. It may also be used in the treatment of von Willebrand's disease and certain types of hemophilia.
Side Effects[edit | edit source]
Common side effects of lypressin include headache, nausea, abdominal pain, and flushing. In rare cases, it can cause more serious side effects such as water intoxication, hyponatremia, and anaphylaxis.
Contraindications[edit | edit source]
Lypressin should not be used in patients with chronic kidney disease, heart failure, or hyponatremia. It should also be used with caution in patients with hypertension.
See Also[edit | edit source]
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