Lys-MDMA

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Chemical compound



Lys-MDMA is a chemical compound that is structurally related to the well-known psychoactive drug MDMA (3,4-methylenedioxy-N-methylamphetamine). It is a derivative of MDMA where the molecule is modified by the addition of a lysine group. This modification is intended to alter the pharmacokinetic properties of the compound, potentially affecting its absorption, distribution, metabolism, and excretion in the body.

Chemical Structure[edit | edit source]

Structure of Lys-MDMA

Lys-MDMA is characterized by the presence of a lysine moiety attached to the MDMA structure. The lysine group is an amino acid that can influence the solubility and bioavailability of the compound. The chemical structure of Lys-MDMA can be represented as a combination of the MDMA core with an additional lysine side chain.

Pharmacology[edit | edit source]

Lys-MDMA is designed to explore the effects of modifying the MDMA molecule with an amino acid. The addition of lysine may affect the way the compound interacts with the serotonin transporter, as well as other neurotransmitter systems in the brain. This could potentially lead to differences in the psychoactive effects, duration of action, and side effect profile compared to MDMA.

Potential Uses[edit | edit source]

Research into Lys-MDMA is primarily focused on understanding how structural modifications can alter the pharmacological properties of MDMA-like compounds. Such studies can provide insights into the development of new therapeutic agents that retain the beneficial effects of MDMA, such as its potential use in psychotherapy, while minimizing adverse effects.

Safety and Legal Status[edit | edit source]

As a research chemical, Lys-MDMA is not approved for medical use and its safety profile is not well-established. It is important to note that the legal status of Lys-MDMA may vary by jurisdiction, and it may be subject to regulation under laws governing controlled substances.

Related Compounds[edit | edit source]

  • MDMA
  • MDA (3,4-methylenedioxyamphetamine)
  • MDEA (3,4-methylenedioxyethylamphetamine)
  • Lysine

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Contributors: Prab R. Tumpati, MD