MED9
MED9 is a gene that encodes a component of the Mediator complex, a coactivator involved in the regulated transcription of nearly all RNA polymerase II-dependent genes. MED9 is involved in the pathway gene transcription, which is part of Gene expression.
Function[edit | edit source]
The MED9 gene is located on the 11th chromosome, with its specific location being 11q13.1. The gene has 5 exons. The MED9 gene encodes a subunit of the mediator complex, a large complex of proteins that functions as a transcriptional coactivator for most RNA polymerase II-transcribed genes.
Clinical significance[edit | edit source]
Mutations in the MED9 gene have been associated with various diseases, including cancer. The gene is overexpressed in several types of cancer, including breast cancer and prostate cancer.
See also[edit | edit source]
References[edit | edit source]
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Contributors: Prab R. Tumpati, MD
