MEN2B
(Redirected from MEN 2B)
MEN2B or Multiple Endocrine Neoplasia Type 2B is a rare autosomal dominant genetic condition that primarily affects the endocrine system. It is characterized by the development of medullary thyroid carcinoma, pheochromocytoma, and multiple mucosal neuromas. MEN2B is a subtype of Multiple Endocrine Neoplasia (MEN), a group of medical disorders that affect the body's endocrine system.
Symptoms[edit | edit source]
The most common symptoms of MEN2B include:
- Medullary thyroid carcinoma
- Pheochromocytoma
- Mucosal neuromas
- Marfanoid habitus
- Intestinal ganglioneuromatosis
Genetics[edit | edit source]
MEN2B is caused by mutations in the RET gene. This gene provides instructions for producing a protein that is involved in signaling within cells. Mutations in the RET gene can lead to the development of tumors in the endocrine system.
Diagnosis[edit | edit source]
Diagnosis of MEN2B is based on clinical features, family history, and genetic testing. Genetic testing can confirm a diagnosis and identify family members who carry the mutation.
Treatment[edit | edit source]
Treatment for MEN2B typically involves surgery to remove the affected glands. Medications may also be used to manage symptoms.
See also[edit | edit source]
MEN2B Resources | ||
---|---|---|
|
|
Translate to: East Asian
中文,
日本,
한국어,
South Asian
हिन्दी,
Urdu,
বাংলা,
తెలుగు,
தமிழ்,
ಕನ್ನಡ,
Southeast Asian
Indonesian,
Vietnamese,
Thai,
မြန်မာဘာသာ,
European
español,
Deutsch,
français,
русский,
português do Brasil,
Italian,
polski
Navigation: Wellness - Encyclopedia - Health topics - Disease Index - Drugs - World Directory - Gray's Anatomy - Keto diet - Recipes
Search WikiMD
Ad.Tired of being Overweight? Try W8MD's physician weight loss program.
Semaglutide (Ozempic / Wegovy and Tirzepatide (Mounjaro) available.
Advertise on WikiMD
WikiMD is not a substitute for professional medical advice. See full disclaimer.
Credits:Most images are courtesy of Wikimedia commons, and templates Wikipedia, licensed under CC BY SA or similar.
Contributors: Prab R. Tumpati, MD