MIR187
MIR187 is a microRNA that is encoded by the MIR187 gene in humans. MicroRNAs (miRNAs) are small non-coding RNA molecules that regulate gene expression post-transcriptionally, playing a crucial role in biological processes such as development, differentiation, and apoptosis.
Function[edit | edit source]
MIR187 is involved in the regulation of various biological processes. It has been found to play a significant role in the immune system, particularly in the regulation of inflammation and immune response. MIR187 achieves this by targeting specific genes and inhibiting their expression, thereby controlling the immune response.
Clinical Significance[edit | edit source]
MIR187 has been implicated in several diseases, including cancer, autoimmune diseases, and infectious diseases. In cancer, MIR187 has been found to act as a tumor suppressor in certain types of cancer, such as breast cancer and colorectal cancer. It achieves this by targeting oncogenes and inhibiting their expression, thereby preventing the uncontrolled cell growth characteristic of cancer.
In autoimmune diseases, MIR187 has been found to play a role in the regulation of the immune response, potentially contributing to the development of these diseases. In infectious diseases, MIR187 has been found to play a role in the immune response to infection, potentially influencing the outcome of the infection.
Research[edit | edit source]
Research into MIR187 is ongoing, with scientists seeking to better understand its function and potential role in disease. This research could potentially lead to the development of new therapeutic strategies for diseases in which MIR187 is implicated.
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Contributors: Prab R. Tumpati, MD