MIR361

MIR361 is a microRNA that is encoded by the MIR361 gene in humans. MicroRNAs (miRNAs) are small non-coding RNA molecules that regulate gene expression post-transcriptionally, playing a crucial role in biological processes such as development, differentiation, and apoptosis.

Function

MIR361 is involved in the regulation of various cellular processes. It functions by binding to the 3' untranslated regions (3' UTRs) of target mRNAs, leading to their degradation or translational repression. This mechanism allows MIR361 to control the expression of numerous genes, influencing cell proliferation, differentiation, and apoptosis.

Clinical Significance

Alterations in the expression of MIR361 have been associated with several types of cancer, including breast cancer, prostate cancer, and colorectal cancer. In these contexts, MIR361 can act either as a tumor suppressor or an oncogene, depending on the specific target genes it regulates.

Research

Research into the role of MIR361 in disease is ongoing, with studies investigating its potential as a diagnostic biomarker and therapeutic target in various types of cancer. Further understanding of the molecular mechanisms underlying MIR361 function could provide valuable insights into the pathogenesis of these diseases and inform the development of novel therapeutic strategies.

See Also

• MicroRNA
• Gene expression
• Cancer