MIR627
MIR627 is a microRNA that is encoded by the MIR627 gene in humans. MicroRNAs (miRNAs) are small non-coding RNA molecules that regulate gene expression post-transcriptionally, playing a crucial role in biological processes such as development, differentiation, and apoptosis.
Function[edit | edit source]
MIR627 is involved in the regulation of gene expression, acting primarily through the inhibition of translation or degradation of mRNAs. It binds to the 3' untranslated region (3' UTR) of target mRNAs and represses their translation. This microRNA has been implicated in various biological processes, including cell proliferation, differentiation, and apoptosis.
Clinical Significance[edit | edit source]
Alterations in the expression of MIR627 have been associated with several human diseases, including cancer. For instance, it has been reported that MIR627 is downregulated in certain types of cancer, suggesting that it may function as a tumor suppressor. Further research is needed to fully understand the role of MIR627 in human disease and its potential as a therapeutic target.
Research[edit | edit source]
Research into the function and clinical significance of MIR627 is ongoing. Current studies are focused on understanding the specific mechanisms by which MIR627 regulates gene expression and its role in disease pathogenesis. This research may lead to the development of new therapeutic strategies for diseases associated with alterations in MIR627 expression.
See Also[edit | edit source]
References[edit | edit source]
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Contributors: Prab R. Tumpati, MD