Mag sulfate

From WikiMD's Food, Medicine & Wellness Encyclopedia

Magnesium Sulfate (or Mag Sulfate) is an inorganic salt (chemical compound) containing magnesium, sulfur and oxygen, with the formula MgSO4. It is often encountered as the heptahydrate sulfate mineral epsomite (MgSO4·7H2O), commonly called Epsom salt.

Chemistry[edit | edit source]

Magnesium sulfate is a small colorless crystal used as an anticonvulsant, a cathartic, and an electrolyte replenisher in the treatment of pre-eclampsia and eclampsia. It causes direct inhibition of action potentials in myometrial muscle cells. Excitation and contraction are uncoupled, which decreases the frequency and force of contractions.

Medical Uses[edit | edit source]

In medicine, magnesium sulfate is used both in the treatment of acute medical problems and for ongoing health issues. For acute cases, it is often given intravenously, typically for the management of severe asthma attacks and acute cardiac dysrhythmias. It is also used as a bronchodilator and smooth muscle relaxant.

For ongoing health issues, magnesium sulfate is used to manage symptoms such as seizures associated with epilepsy, hypomagnesemia, and asthma. It is also used in obstetrics for the management of pre-eclampsia and eclampsia.

Safety[edit | edit source]

While generally safe for use at recommended doses, magnesium sulfate can cause a variety of side effects including a warm feeling, vomiting, sedation, confusion, and other side effects. In rare cases, more severe side effects such as allergic reactions or life-threatening complications can occur.

See Also[edit | edit source]



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Contributors: Prab R. Tumpati, MD