Magnesium glycinate

From WikiMD's Wellness Encyclopedia

Magnesium glycinate, also known as magnesium bisglycinate or magnesium diglycinate, is a chelated form of magnesium in which magnesium is bound to glycine, an amino acid. This form of magnesium supplementation has gained popularity due to its high bioavailability and gentle effect on the gastrointestinal tract, making it a preferred choice for individuals seeking to increase their magnesium intake without experiencing the laxative effects commonly associated with other forms of magnesium supplements.

Overview[edit | edit source]

Magnesium is an essential mineral crucial for numerous biochemical reactions in the body. It plays a key role in energy production, nerve function, muscle contraction, and the maintenance of normal heart rhythm. Despite its importance, magnesium deficiency is relatively common, leading to a variety of health issues.

Magnesium glycinate is considered one of the most bioavailable forms of magnesium, meaning that it is more easily absorbed and utilized by the body compared to other forms, such as magnesium oxide or magnesium citrate. The presence of glycine increases magnesium's solubility and absorption in the intestines, enhancing its effectiveness as a supplement.

Health Benefits[edit | edit source]

Magnesium glycinate has been associated with several health benefits, including:

  • Improved Sleep: Magnesium plays a role in regulating melatonin levels and relaxing the muscles, which can contribute to better sleep quality.
  • Anxiety Reduction: Some studies suggest that magnesium glycinate can have a calming effect on the brain, potentially reducing symptoms of anxiety.
  • Bone Health: Magnesium is vital for bone health, working in conjunction with calcium and vitamin D to support bone density.
  • Heart Health: Adequate magnesium intake is linked to a lower risk of cardiovascular disease, as it helps maintain normal heart rhythms and blood pressure levels.
  • Blood Sugar Control: Magnesium plays a role in glucose metabolism, and magnesium glycinate supplementation may help improve insulin sensitivity and blood sugar control.

Side Effects[edit | edit source]

While magnesium glycinate is generally well-tolerated, some individuals may experience mild side effects, such as nausea, diarrhea, or stomach cramps. These effects are less common and less severe than those associated with other forms of magnesium supplements.

Dosage and Administration[edit | edit source]

The recommended dietary allowance (RDA) for magnesium varies by age, sex, and life stage. It is important to consult with a healthcare provider to determine the appropriate dosage of magnesium glycinate, especially for individuals with kidney disease or those taking medications that may interact with magnesium.

Conclusion[edit | edit source]

Magnesium glycinate is a highly bioavailable and gentle form of magnesium supplementation, offering a range of health benefits with minimal side effects. It can be an effective option for individuals looking to address magnesium deficiency and improve their overall health.


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Contributors: Prab R. Tumpati, MD