Malignant angioendotheliomatosis

Malignant angioendotheliomatosis (MAE) is a rare form of cancer that affects the blood vessels. It is characterized by the proliferation of malignant endothelial cells within small blood vessels, leading to the obstruction of these vessels and subsequent tissue necrosis.

Symptoms

The symptoms of malignant angioendotheliomatosis can vary widely, depending on the organs affected. Common symptoms include fever, fatigue, weight loss, and neurological symptoms such as confusion, seizures, and paralysis. In some cases, the disease may also cause skin lesions.

Diagnosis

Diagnosis of malignant angioendtheliomatosis is often challenging due to its rarity and nonspecific symptoms. It is typically confirmed through a biopsy of affected tissue, which is examined under a microscope to identify the presence of malignant endothelial cells. Other diagnostic tests may include blood tests, imaging studies, and lumbar puncture.

Treatment

Treatment for malignant angioendtheliomatosis typically involves chemotherapy to kill the malignant cells. In some cases, radiation therapy may also be used. The choice of treatment depends on the extent of the disease and the patient's overall health.

Prognosis

The prognosis for malignant angioendtheliomatosis is generally poor, with a median survival time of less than one year. However, early detection and treatment can improve survival rates.

See also

• Angioendotheliomatosis
• Endothelial cell
• Cancer

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