Meningioangiomatosis

Meningioangiomatosis is a rare, benign, hamartomatous lesion of the central nervous system (CNS). It is characterized by a proliferation of meningothelial cells, blood vessels, and neural elements. The condition is often associated with neurofibromatosis type 2 (NF2), but can also occur sporadically.

Clinical Presentation[edit | edit source]

Patients with meningioangiomatosis often present with seizures, headache, and focal neurological deficits. The age of onset varies, but the condition is most commonly diagnosed in children and young adults.

Pathology[edit | edit source]

Meningioangiomatosis is characterized by a proliferation of meningothelial cells, blood vessels, and neural elements. The lesion is often located in the cerebral cortex and leptomeninges, but can also occur in the spinal cord. Histologically, the lesion resembles a meningioma, but with a more complex architecture.

Diagnosis[edit | edit source]

The diagnosis of meningioangiomatosis is typically made based on histopathological examination of a biopsy specimen. Magnetic resonance imaging (MRI) can also be helpful in the diagnosis, as the lesion often shows a characteristic appearance on imaging.

Treatment[edit | edit source]

The treatment of meningioangiomatosis typically involves surgical resection of the lesion. In some cases, antiepileptic drugs may also be used to control seizures.

Prognosis[edit | edit source]

The prognosis for patients with meningioangiomatosis is generally good, as the lesion is benign and often responds well to treatment. However, the condition can be associated with significant morbidity due to seizures and other neurological deficits.

See Also[edit | edit source]

Meningioangiomatosis Resources
Need Help Finding a Doctor? Need help finding a doctor or specialist anywhere in the world? Explore our world directory. WikiMD's DocFinder can assist you in locating millions of physicians.	Medical Knowledge Access the latest research - Most recent articles Ongoing trials.