Mepindolol
Mepindolol is a beta blocker used in the treatment of hypertension and angina pectoris. It is a non-selective beta blocker, meaning it blocks both beta-1 and beta-2 adrenergic receptors.
Pharmacology[edit | edit source]
Mepindolol works by blocking the action of epinephrine and norepinephrine, two hormones that stimulate the heart and blood vessels. By blocking these hormones, mepindolol reduces heart rate, decreases blood pressure, and helps to prevent angina attacks.
Clinical Use[edit | edit source]
Mepindolol is primarily used to treat hypertension and angina pectoris. It may also be used to prevent myocardial infarction (heart attack) in patients with certain risk factors.
Side Effects[edit | edit source]
Common side effects of mepindolol include fatigue, dizziness, and cold hands and feet. Less common side effects can include shortness of breath, slow heart rate, and low blood pressure.
Contraindications[edit | edit source]
Mepindolol is contraindicated in patients with severe bradycardia, heart block, or cardiogenic shock. It should also be used with caution in patients with asthma or other respiratory conditions, as it can cause bronchospasm.
Interactions[edit | edit source]
Mepindolol can interact with a number of other medications, including other blood pressure medications, heart medications, and certain antidepressants. It is important for patients to inform their healthcare provider of all medications they are currently taking.
See Also[edit | edit source]
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Contributors: Prab R. Tumpati, MD