Meprednisone

Meprednisone is a glucocorticoid used in the treatment of various inflammatory diseases and certain types of cancer. It is a prodrug of prednisone and is activated in the body by the liver.

Pharmacology

Meprednisone is a synthetic glucocorticoid, which is a class of corticosteroids that are involved in a wide range of physiological processes including the regulation of inflammation, immune response, and carbohydrate metabolism. It is a prodrug, meaning it is inactive until metabolized by the body. In the case of meprednisone, it is converted into the active drug prednisone by the liver.

Medical uses

Meprednisone is used to treat a variety of conditions that involve inflammation. These include rheumatoid arthritis, lupus, asthma, and allergic reactions. It is also used in the treatment of certain types of cancer, including leukemia and lymphoma.

Side effects

Like all glucocorticoids, meprednisone can have a number of side effects. These can include weight gain, osteoporosis, glaucoma, and Cushing's syndrome. It can also suppress the immune system, leading to an increased risk of infection.

History

Meprednisone was first synthesized in the 1950s as part of a search for more effective glucocorticoid drugs. It is now widely used around the world.

See also

• Prednisone
• Corticosteroids
• Glucocorticoids

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