Metaescaline

From WikiMD's Food, Medicine & Wellness Encyclopedia

Metaescaline‏‎ (also known as 3,4,5-trimethoxy-4-ethylphenethylamine) is a psychedelic and hallucinogenic drug, which is structurally related to mescaline. It was first synthesized by Alexander Shulgin, a renowned chemist and psychopharmacologist.

History[edit | edit source]

Metaescaline was first synthesized and documented by Alexander Shulgin in his book PiHKAL (Phenethylamines I Have Known And Loved). Shulgin's research has contributed significantly to the understanding of the pharmacology of phenethylamine derivatives.

Pharmacology[edit | edit source]

Metaescaline is a phenethylamine, but its pharmacological action is not fully understood. It is believed to act as a serotonin receptor agonist, similar to other psychedelic drugs. This means it binds to and activates certain serotonin receptors in the brain, which can lead to altered perceptions and hallucinations.

Effects[edit | edit source]

The effects of metaescaline can vary greatly depending on the dose, individual physiology, and set and setting. Common effects reported include visual hallucinations, enhanced colors, altered thought processes, and a sense of euphoria. Some users also report experiencing negative effects such as nausea, anxiety, and confusion.

Legal Status[edit | edit source]

The legal status of metaescaline varies by country. In the United States, it is not specifically listed as a controlled substance, but it could potentially be considered an analog of mescaline, which is a Schedule I drug under the Controlled Substances Act.

See Also[edit | edit source]

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Contributors: Prab R. Tumpati, MD