Methadone maintenance

From WikiMD's Wellness Encyclopedia

Methadone Maintenance is a medical treatment involving the use of the synthetic opioid methadone to treat opioid dependence. This treatment method is often used for individuals who have developed a dependence on heroin or other opioids.

History[edit | edit source]

Methadone maintenance treatment (MMT) was first developed in the 1960s by Dole and Nyswander. They discovered that methadone, a synthetic opioid, could be used to effectively manage opioid dependence. This was a significant breakthrough in the field of addiction medicine.

Treatment[edit | edit source]

Methadone maintenance treatment involves the administration of methadone to individuals who are dependent on opioids. The methadone is usually given in a controlled clinical setting, and the dosage is carefully monitored by a healthcare professional. The goal of MMT is to reduce the individual's dependence on opioids and to help them lead a more stable and productive life.

Effectiveness[edit | edit source]

Numerous studies have shown that methadone maintenance treatment is effective in reducing opioid use and related harms. It has been found to decrease illicit drug use, reduce criminal activity, improve physical and mental health, and enhance social functioning.

Risks and Side Effects[edit | edit source]

Like all medications, methadone can have side effects. These can include constipation, drowsiness, and dry mouth. In rare cases, methadone can cause serious side effects such as respiratory depression and cardiac arrhythmias. It is important for individuals receiving MMT to be closely monitored by a healthcare professional.

See Also[edit | edit source]

References[edit | edit source]

Methadone maintenance Resources
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Contributors: Prab R. Tumpati, MD